High Quality Peptide Powder PT-141 (CAS: 32780-32-8)
|10-49 50-99 100+|
|FOB Unit Price:||US $2.5 US $2.3 US $2|
|Purchase Qty. (gram)||FOB Unit Price|
|Production Capacity:||500 Kg /Month|
|Payment Terms:||T/T, D/P, Western Union, Money Gram, Bitcoin;Bank Transfer|
- Model NO.: 32780-32-8
- Customized: Customized
- Suitable for: Adult
- Purity: >98%
- Molecular Formula: C7h15no4
- Refractive Index: 1.544
- Trademark: Sinosteroids
- Specification: SGS, ISO9001, GMP
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Powder
- CAS No: 32780-32-8
- Molecular Weight: 177.20
- Flash Point: 162.8oc
- Transport Package: Foil Bag
- Origin: China
English Synonyms:1-Amino-1,5,6-trideoxy-5-(hydroxymethyl)-D-chiro-inositol;PT141 Acetate;(1R,2S,3S,4S,6R)-4-amino-6-(methoxymethyl)cyclohexane-1,2,3-triol;PT-141;1D-1-amino-1,5,6-trideoxy-5-(hydroxymethyl)-chiro-inositol;D-chiro-Inositol, 1-amino-1,5,6-trideoxy-5-(hydroxymethyl)-;(1R,2S,3S,4S,6R)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol;D-chiro-Inositol,1-amino-1,5,6-trideoxy-5- (hydroxymethyl)-;PT141;Bremelanotide (PT-141);(1R,2S,3S,4S)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol;Validamine PT 141 Acetate;Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH;PT-141 (Bremelanotide);
Molecular formula: C7H15NO4
Molecular Weight: 177.20
Boiling point: 345.6 ° C at 760 mmHg
Refractive index: 1.544
Flash point: 162.8 ° C
Density: 1.434 g / cm3
PT-141, the first in a new class of therapies called melanocortin agonists, works through a mechanism of action involving the central nervous system rather than directly on the vascular system. As a result,it may offer significant safety and efficacy benefits over currently available products, which belong to the class of phosphodiesterase-5 (PDE-5) inhibitors.
PT-141 is nasally administered and is both non-invasive and fast acting. Importantly, PT-141 is not expected to be contraindicated in patients taking nitrates for the treatment of cardiovascular disease. Clinical studies have demonstrated PT-141 to be safe and effective and to improve patient experience.
|Appearance||White powder||White powder|
|Solubility||Soluble in water or 10% acetic acid to give a clear, colorless solution||Conforms|
|Amino Acid Composition||±10% of theoretical||Conforms|
|Related Substance(By HPLC)||Total Impurities(%) 3.0% Largest Single Impurity(%) 1.0%||1.1% 0.3%|
|Acetate Content(By HPLC)||15.0%||8.0%|
|Water Content(Karl Fischer)||<8.0%||3.5%|
|Peptide content(N determination)||≥80.0%||87.8%|
|Bacterial Endotoxins||< 5 EU/mg||Conforms|
|Peptide Putity(By HPLC)||≥97% by area integration||98.9%|
PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). PT-141 was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alpha-Melanocyte stimulating hormone. MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido. Resultantly, PT-141 has been shown in studies to exhibit libido-enhancing effects by activating the melanocortin receptors MC1R and MC4R, but not skin tanning. Melanotan 1 and Melanotan 2 have been researched for their use in protecting against the harmful effects of ultraviolet radiation from sunlight due to their melanogenesis-stimulating properties.
PT-141 is a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction. Studies have shown that PT-141 does not act on the vascular system like former compounds, but allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation.
PT-141 is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger.
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