Delta Sleep Inducing Peptide Dsip/CAS 62568-57-4
|FOB Price:||US $1 / Piece|
|Min. Order:||1 Piece|
|Min. Order||FOB Price|
|1 Piece||US $1/ Piece|
|Production Capacity:||10000vials /Month|
|Transport Package:||According to Your Requirement|
|Payment Terms:||L/C, T/T, D/P, Paypal, Money Gram, Western Union|
- Model NO.: CAS: 62568-57-4
- Customized: Customized
- Suitable for: Adult
- Purity: >99%
- Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
- MW: 848.813620
- Specification: 5mg/Vial, 10vial/Kit, SGS, ISO9001, KOSHER
- Place of Origin: China
- Origin: China
- Powder: Yes
- Certification: GMP, HSE, ISO 9001, USP, BP
- State: Solid
- CAS: 62568-57-4
- Mf: C35h48n10o15
- Disp Purity: 99%
- Appearance: White Lyophilized Powder
- Trademark: HBU
- HS Code: 2937290023
Dsip, Delta Sleep-Inducing Peptide, Polypeptide Hormones
(Delta sleep-inducing peptide)
Alias: Delta Sleep Inducing Peptide
Specification: 5mg/vial ,10vial/kit
Appearance: White Lyophilized Powder
Place of Origin: China
Method of Analysis: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.
DSIP (Delta Sleep-inducing Peptide) is a neuropeptide found in the hypothalamus, pituitary, and adrenal glands. Its isolation has allowed for extensive research which has found several possible primary and peripheral roles of this peptide. First, DSIP has been shown to induce sleep. Second, it may have benefits as an analgesic in treatment of chronic pain, sometimes as an adjunct treatment. Third, DSIP has been shown to block ACTH release and decrease levels of ACTH, stimulate LH release, and act as an inhibitor of the secretion of somatostatin. The source of production of DSIP is yet unknown; It may be produced in the central nervous system or in a peripheral organ. It is thought to pass
Through the blood-brain barrier (BBB) more easily than most known neuropeptides. As mentioned, DSIP has shown positive results in inducing slow-wave EEG (sleep). It has been shown to help treat narcolepsy and restore disturbed sleep patterns to normal sleep rhythms.
Since the turn of the century, it has been postulated that humoral factors induce sleep. Many compounds were proposed as sleep-factors, but only two of the sleep-peptides have been purified to homogeneity and characterized, so far. One of them, DSIP, was shown to be a nonapeptide of MW 849 and to induce mainly delta-sleep in rabbits, rats, mice, and humans, whereas in cats, the effect on REM sleep was more pronounced. A U-shaped activity curve was determined for the dose as well as for the time of infusion. DSIP-like material was found by RIA and immunohistochemistry in brain and by RIA in peripheral organs of the rat as well as in plasma of several mammals. In addition to sleep, the peptide also has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal.
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